Recent advances in myeloid-derived suppressor cell biology

Entosis: From Cell Biology to Medical Most cancers Pathology 

Entosis is a phenomenon, through which one cell enters a second one. New clinico-histopathological research of entosis prompted us to summarize its significance in most cancers. It seems that entosis is perhaps a novel, unbiased prognostic predictor think about most cancers histopathology.

We briefly talk about the organic foundation of entosis, adopted by a abstract of revealed clinico-histopathological research on entosis significance in most cancers prognosis. The correlation of entosis with most cancers prognosis in head and neck squamous cell carcinoma, anal carcinoma, lung adenocarcinoma, pancreatic ductal carcinoma and breast ductal carcinoma, is proven.

Quite a few entotic figures are related to a extra malignant most cancers phenotype and poor prognosis in lots of cancers. We additionally confirmed that some anticancer medicine may induce entosis in cell tradition, at the same time as an escape mechanism. Thus, entosis is probably going useful for survival of malignant cells, i.e., an entotic cell can disguise from unfavourable components in one other cell and subsequently depart the host cell remaining intact, resulting in failure in remedy or most cancers recurrence.

Lastly, we spotlight the potential relationship of cell adhesion with entosis in vitro, based mostly on the mannequin of the BxPc3 cells cultured in full adhesive circumstances, evaluating them to a generally used MCF7 semiadhesive mannequin of entosis.

 

K-Ras Activation Assay Kit, Trial Size

STA-400-K-T 5 assays
EUR 483.6
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

N-Ras Activation Assay Kit, Trial Size

STA-400-N-T 5 assays
EUR 483.6
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

Ral Activation Assay

STA-408 20 assays
EUR 908.4
Description: Our Ral Activation Assay uses visible agarose beads to selectively precipitate the active form of Ral protein. The precipitated small GTPase is then detected by Western blot using a Ral-specific antibody included in the kit.

Ran Activation Assay

STA-409 20 assays
EUR 908.4
Description: Our Ran Activation Assay uses visible agarose beads to selectively precipitate the active form of Ran protein. The precipitated small GTPase is then detected by Western blot using a Ran-specific antibody included in the kit.

Rac1 Activation Assay

STA-401-1 20 assays
EUR 665

Rac2 Activation Assay

STA-401-2 20 assays
EUR 665

RhoA Activation Assay

STA-403-A 20 assays
EUR 665

RhoB Activation Assay

STA-403-B 20 assays
EUR 908.4
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoC Activation Assay

STA-403-C 20 assays
EUR 908.4
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

Arf1 Activation Assay

STA-407-1 20 assays
EUR 665

Arf6 Activation Assay

STA-407-6 20 assays
EUR 908.4
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Cdc42 Activation Assay

STA-402 20 assays
EUR 665

Rap1 Activation Assay Kit

STA-406-1 20 assays
EUR 665

Rap2 Activation Assay Kit

STA-406-2 20 assays
EUR 908.4
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

RalA Activation Assay Biochem Kit

BK040 KIT 50 assays Ask for price

Arf1 Pulldown Activation Assay Kit

BK032-S KIT 20 assays
EUR 540.8

Arf6 Pulldown Activation Assay Kit

BK033-S KIT 20 assays
EUR 540.8

Rac1 Pulldown Activation Assay Kit

BK035 KIT 50 assays
EUR 890.24

Rac1 Pulldown Activation Assay Kit

BK035-S KIT 20 assays
EUR 409.76

RhoA Pulldown Activation Assay Kit

BK036 KIT 80 assays
EUR 890.24

RhoA Pulldown Activation Assay Kit

BK036-S KIT 20 assays
EUR 409.76

Cdc42 Pulldown Activation Assay Kit

BK034 KIT 50 assays
EUR 890.24

Cdc42 Pulldown Activation Assay Kit

BK034-S KIT 20 assays
EUR 409.76

Rac1 G-LISA Activation Assay Kit

BK126 KIT 96 assays
EUR 1036.88

Ral Activation Assay Kit, Trial Size

STA-408-T 5 assays
EUR 483.6
Description: Our Ral Activation Assay uses visible agarose beads to selectively precipitate the active form of Ral protein. The precipitated small GTPase is then detected by Western blot using a Ral-specific antibody included in the kit.

Ran Activation Assay Kit, Trial Size

STA-409-T 5 assays
EUR 483.6
Description: Our Ran Activation Assay uses visible agarose beads to selectively precipitate the active form of Ran protein. The precipitated small GTPase is then detected by Western blot using a Ran-specific antibody included in the kit.

Rac1 Activation Assay Kit, Trial Size

STA-401-1-T 5 assays
EUR 483.6
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Rac2 Activation Assay Kit, Trial Size

STA-401-2-T 5 assays
EUR 483.6
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

RhoA Activation Assay Kit, Trial Size

STA-403-A-T 5 assays
EUR 483.6
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoB Activation Assay Kit, Trial Size

STA-403-B-T 5 assays
EUR 483.6
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoC Activation Assay Kit, Trial Size

STA-403-C-T 5 assays
EUR 483.6
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

Rap1 Activation Assay Kit, Trial Size

STA-406-1-T 5 assays
EUR 483.6
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Rap2 Activation Assay Kit, Trial Size

STA-406-2-T 5 assays
EUR 483.6
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Arf1 Activation Assay Kit, Trial Size

STA-407-1-T 5 assays
EUR 483.6
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Arf6 Activation Assay Kit, Trial Size

STA-407-6-T 5 assays
EUR 483.6
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Cdc42 Activation Assay Kit, Trial Size

STA-402-T 5 assays
EUR 483.6
Description: Our Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of Cdc42 protein. The precipitated small GTPase is then detected by Western blot using a Cdc42-specific antibody included in the kit.

Rac1/Cdc42 Activation Assay Combo Kit

STA-404 2 x 20 assays
EUR 975

RhoA G-LISA Activation Assay (luminescence)

BK121 KIT 96 assays
EUR 1036.88

RhoA G-LISA Activation Assay (colorimetric)

BK124 KIT 96 assays
EUR 1036.88

RhoA G-LISA Activation Assay (colorimetric)

BK124-S KIT 24 assays
EUR 626.08

RhoA G-LISA Activation Assay (colorimetric)

BK124-XL Large Quantities Ask for price

Combo RhoA/Rac1/Cdc42 Activation Assay Kit

BK030 KIT 3 x 10 assays
EUR 1098.24

RhoA/Rac1/CDC42 Activation Assay Combo Kit

STA-405 3 x 10 assays
EUR 975

Rac1,2,3 G-LISA Activation Assay Kit (colorimetric)

BK125 KIT 96 assays
EUR 1036.88

Rac1 G-LISA Activation Assay Kit (colorimetric)

BK128 KIT 96 assays
EUR 1036.88

Rac1 G-LISA Activation Assay Kit (colorimetric)

BK128-S KIT 24 assays
EUR 626.08

RalA G-LISA Activation Assay Kit (colorimetric)

BK129 KIT 96 assays
EUR 1036.88

Cdc42 G-LISA Activation Assay Kit (colorimetric)

BK127 KIT 96 assays
EUR 1036.88

Cdc42 G-LISA Activation Assay Kit (colorimetric)

BK127-S KIT 24 assays
EUR 626.08

Trypsinogen Activation Peptide (TAP) Magnetic Luminex Assay Kit

LKU603513-96T 96T
EUR 944.2

Trypsinogen Activation Peptide (TAP) Magnetic Luminex Assay Kit

LKU603521-96T 96T
EUR 894.7

Trypsinogen Activation Peptide (TAP) Magnetic Luminex Assay Kit

LKU603531-96T 96T
EUR 869.4

Lymphocyte Activation Gene 3 (LAG3) Magnetic Luminex Assay Kit

LKU607300-96T 96T
EUR 917.7

Lymphocyte Activation Gene 3 (LAG3) Magnetic Luminex Assay Kit

LKU607304-96T 96T
EUR 944.2

Fibroblast Activation Protein Alpha (FAPa) Magnetic Luminex Assay Kit

LKU601220-96T 96T
EUR 993.6

Fibroblast Activation Protein Alpha (FAPa) Magnetic Luminex Assay Kit

LKU601221-96T 96T
EUR 966

Fibroblast Activation Protein Alpha (FAPa) Magnetic Luminex Assay Kit

LKU601222-96T 96T
EUR 1048.8

Linker For Activation Of T-Cell (LAT) Magnetic Luminex Assay Kit

LKU601732-96T 96T
EUR 869.4

Thymus Activation Regulated Chemokine (TARC) Magnetic Luminex Assay Kit

LKU603970-96T 96T
EUR 995.9

Thymus Activation Regulated Chemokine (TARC) Magnetic Luminex Assay Kit

LKU603977-96T 96T
EUR 944.2

Thymus Activation Regulated Chemokine (TARC) Magnetic Luminex Assay Kit

LKU603996-96T 96T
EUR 869.4

B-Cell Activation Factor Receptor (BAFFR) Magnetic Luminex Assay Kit

LKU603426-96T 96T
EUR 869.4

Activation Induced Cytidine Deaminase (AICDA) Magnetic Luminex Assay Kit

LKU606582-96T 96T
EUR 966

Pulmonary Activation Regulated Chemokine (PARC) Magnetic Luminex Assay Kit

LKU605817-96T 96T
EUR 770.5

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Magnetic Luminex Assay Kit

LKU603761-96T 96T
EUR 966

96-Well Ras Activation ELISA Kit (Colorimetric)

STA-440 96 assays
EUR 810

B-Lymphocyte Activation Antigen B7-1 (LAB7-1) Magnetic Luminex Assay Kit

LKU603336-96T 96T
EUR 917.7

96-Well Ras Activation ELISA Kit (Chemiluminescent)

STA-441 96 assays
EUR 810

T-Cell Activation Antigen, Increased Late Expression (TACTILE) Magnetic Luminex Assay Kit

LKU604679-96T 96T
EUR 966

Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) Magnetic Luminex Assay Kit

LKU603532-96T 96T
EUR 966

Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) Magnetic Luminex Assay Kit

LKU603538-96T 96T
EUR 966

V-Set Domain Containing T-Cell Activation Inhibitor 1 (VTCN1) Magnetic Luminex Assay Kit

LKU603615-96T 96T
EUR 966

Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAq) Magnetic Luminex Assay Kit

LKU607555-96T 96T
EUR 993.6

Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz) Magnetic Luminex Assay Kit

LKU607558-96T 96T
EUR 993.6

Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Epsilon (YWHAe) Magnetic Luminex Assay Kit

LKU607552-96T 96T
EUR 966

Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) Magnetic Luminex Assay Kit

LKU600254-96T 96T
EUR 993.6

Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) Magnetic Luminex Assay Kit

LKU607693-96T 96T
EUR 770.5

Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) Magnetic Luminex Assay Kit

LKU607695-96T 96T
EUR 770.5

Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) Magnetic Luminex Assay Kit

LKU607696-96T 96T
EUR 770.5

Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) Magnetic Luminex Assay Kit

LKU607697-96T 96T
EUR 993.6

Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) Magnetic Luminex Assay Kit

LKU607698-96T 96T
EUR 1043.1

CORNING® BIOCOAT™ T-CELL ACTIVATION CONTROL 96 WELL FLAT BOTTOM ASSAY PLATE, INDIVIDUALLY WRAPPED, 5/CASE

354730 5/pk
EUR 102
Description: Advanced Cells - DL; BioCoat 96 Well Clear - DL

CORNING® BIOCOAT™ T-CELL ACTIVATION ANTI-MOUSE CD3 96 WELL FLAT BOTTOM ASSAY PLATE, INDIVIDUALLY WRAPPED, 5/CASE

354720 5/pk
EUR 576
Description: Advanced Cells - DL; BioCoat 96 Well Clear - DL

CORNING® BIOCOAT™ T-CELL ACTIVATION ANTI-HUMAN CD3 96 WELL FLAT BOTTOM ASSAY PLATE, INDIVIDUALLY WRAPPED, 5/CASE

354725 5/pk
EUR 568.8
Description: Advanced Cells - DL; BioCoat 96 Well Clear - DL

NFAT activation molecule 1

AP85978 1mg
EUR 2640

NFAT activation molecule 1

AP86130 1mg
EUR 2640

Early activation antigen CD69

AP81561 1mg
EUR 2640

Early activation antigen CD69

AP81836 1mg
EUR 2640

Stat3 Activation Inhibitor, SPI

1813-2 each
EUR 274.8

CD3 (activation epitope) Antibody

abx139107-01mg 0.1 mg
EUR 460.8

GAL4 Activation Domain Antibody

20-abx330273
  • Ask for price
  • Ask for price
  • 100 ug
  • 50 ug

CD3 (activation epitope) Antibody

abx139107-100l 100 µl
EUR 300

CD3 (activation epitope) Antibody

abx139107-500l 500 µl Ask for price

CD18 (Activation Epitope) Antibody

GWB-9C757A 0.02 mg Ask for price

CD18 (Activation Epitope) Antibody

GWB-778F3E 0.2 mg Ask for price

CD11b activation epitope Antibody

abx140366-01mg 0.1 mg
EUR 427.2

CD11b activation epitope Antibody

abx140396-01mg 0.1 mg
EUR 427.2

CD11b activation epitope Antibody

abx140366-100g 100 µg
EUR 275

CD11b activation epitope Antibody

abx140396-100g 100 µg
EUR 275

Trypsinogen Activation Peptide,TAP

AP79714 1mg
EUR 2640

Trypsinogen Activation Peptide,TAP

AP79935 1mg
EUR 2640

NF-κB Activation Inhibitor III

C3559-25 25 mg
EUR 325
Description: NF-κB inhibitor

NF-κB Activation Inhibitor III

C3559-5 5 mg
EUR 77
Description: NF-κB inhibitor

GAL4 Activation Domain Rabbit pAb

E2350167 100ul
EUR 225
Description: Available in various conjugation types.

EZAct? Procathepsin Activation Buffer

1030-1 each
EUR 183.6

CD3 (activation epitope) Antibody (PE)

abx139119-01mg 0.1 mg
EUR 577.2

CD3 (activation epitope) Antibody (PE)

abx139119-100l 100 µl
EUR 400

CD3 (activation epitope) Antibody (PE)

abx139119-500l 500 µl Ask for price

CD3 activation epitope Antibody (APC)

abx140478-01mg 0.1 mg
EUR 577.2

CD3 activation epitope Antibody (APC)

abx140478-100g 100 µg
EUR 400

CD11b Activation Epitope Antibody (PE)

abx140359-100tests 100 tests
EUR 577.2

CD3 activation epitope Antibody (FITC)

abx140488-01mg 0.1 mg
EUR 510

Cd18 (Activation Epitope) Antibody (RPE)

GWB-17EC2C 100 TESTS Ask for price

CD18 (Activation Epitope) Antibody (RPE)

GWB-Q01003 25 TESTS Ask for price

anti-Lymphocyte Activation Gene 3

YF-PA12911 100 ug
EUR 483.6
Description: Rabbit polyclonal to Lymphocyte Activation Gene 3

CD11b Activation Epitope Antibody (PE)

abx140359-100g 100 µg
EUR 400

CD3 activation epitope Antibody (FITC)

abx140488-100g 100 µg
EUR 350

Activation-induced cytidine deaminase

AP80386 1mg
EUR 2640

Lymphocyte activation gene 3 protein

AP84383 1mg
EUR 2640

Lymphocyte activation gene 3 protein

AP84823 1mg
EUR 2640

Lymphocyte activation gene 3 protein

AP85011 1mg
EUR 2640

Cd18 (Activation Epitope) Antibody (FITC)

GWB-550993 0.025 mg Ask for price

Cd18 (Activation Epitope) Antibody (FITC)

GWB-56BD51 0.1 mg Ask for price

Active Lymphocyte Activation Gene 3 (LAG3)

APB663Mu61 10ug
EUR 300

Active Lymphocyte Activation Gene 3 (LAG3)

APB663Ra61 10ug
EUR 239

Lymphocyte Activation Gene 3 Antibody

DF13960 100ul
EUR 420

Lymphocyte Activation Gene 3 Antibody

DF13960-100ul 100ul
EUR 280

Lymphocyte Activation Gene 3 Antibody

DF13960-200ul 200ul
EUR 350

Lymphocyte Activation Gene 3 Antibody

DF14459 100ul
EUR 420

Lymphocyte Activation Gene 3 Antibody

DF14459-100ul 100ul
EUR 280

Lymphocyte Activation Gene 3 Antibody

DF14459-200ul 200ul
EUR 350

T-lymphocyte activation antigen CD86

AP78680 1mg
EUR 2640

T-lymphocyte activation antigen CD80

AP79265 1mg
EUR 2640

T-lymphocyte activation antigen CD80

AP81755 1mg
EUR 2640

T-lymphocyte activation antigen CD86

AP81806 1mg
EUR 2640

Anti-GAL4 Activation Domain antibody

STJ97427 200 µl
EUR 236.4
Description: Rabbit polyclonal to GAL4 Activation Domain.

Anti-Hu CD11b (activation epitope) PE

1P-172-T025 25 tests
EUR 121

Anti-Hu CD11b (activation epitope) PE

1P-172-T100 100 tests
EUR 242

Rat Calpain Activation-1 (CAPNA1) Elisa Kit

YLA1388RA-48T 48T Ask for price

Rat Calpain Activation-1 (CAPNA1) Elisa Kit

YLA1388RA-96T 96T Ask for price

Thrombin Activation peptide fragment 1

E8ER1917-70 100ul
EUR 275
Description: Available in various conjugation types.

Cd18 (Activation Epitope) Antibody (Biotin)

GWB-AB34A9 0.1 mg Ask for price

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody

20-abx128336
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody

20-abx173814
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody

abx128336-100l 100 µl
EUR 275

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody

abx128336-1ml 1 ml
EUR 750

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody

abx128336-200l 200 µl
EUR 337.5

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody

abx173814-100l 100 µl
EUR 787.5

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody

abx173814-1ml 1 ml Ask for price

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody

abx173814-200l 200 µl Ask for price

AP-1/NF-κB activation inhibitor 1

T9656-10mg 10mg Ask for price
Description: AP-1/NF-κB activation inhibitor 1

AP-1/NF-κB activation inhibitor 1

T9656-1g 1g Ask for price
Description: AP-1/NF-κB activation inhibitor 1

AP-1/NF-κB activation inhibitor 1

T9656-1mg 1mg Ask for price
Description: AP-1/NF-κB activation inhibitor 1

AP-1/NF-κB activation inhibitor 1

T9656-50mg 50mg Ask for price
Description: AP-1/NF-κB activation inhibitor 1

AP-1/NF-κB activation inhibitor 1

T9656-5mg 5mg Ask for price
Description: AP-1/NF-κB activation inhibitor 1

Recombinant Neutral Sphingomyelinase Activation Associated Factor (NSMAF)

RPE042Hu01 10ug
EUR 164

Recombinant Neutral Sphingomyelinase Activation Associated Factor (NSMAF)

4-RPE042Hu01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Neutral Sphingomyelinase Activation Associated Factor expressed in: E.coli

Recombinant Neutral Sphingomyelinase Activation Associated Factor (NSMAF)

RPU51861-100ug 100ug
EUR 504.9

Recombinant Neutral Sphingomyelinase Activation Associated Factor (NSMAF)

RPU51861-1mg 1mg
EUR 2238.6

Recombinant Neutral Sphingomyelinase Activation Associated Factor (NSMAF)

RPU51861-50ug 50ug
EUR 405.9

Anti-CD3 epsilon (activation epitope) PE

1P-599-C025 0.025 mg
EUR 121

Anti-CD3 epsilon (activation epitope) PE

1P-599-C100 0.1 mg
EUR 242

Non-T-cell Activation Linker Protein

20-abx260597
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 25 ug
  • 5 ug

Non-T-cell Activation Linker Protein

abx260597-200g 200 µg
EUR 325

Non-T-cell Activation Linker Protein

abx260597-50g 50 µg
EUR 225

Rat B Cell Activation Factor ELISA kit

E02B0309-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat B Cell Activation Factor ELISA kit

E02B0309-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat B Cell Activation Factor ELISA kit

E02B0309-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig B Cell Activation Factor ELISA kit

E07B0309-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig B Cell Activation Factor ELISA kit

E07B0309-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig B Cell Activation Factor ELISA kit

E07B0309-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog B Cell Activation Factor ELISA kit

E08B0309-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog B Cell Activation Factor ELISA kit

E08B0309-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog B Cell Activation Factor ELISA kit

E08B0309-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat B Cell Activation Factor ELISA kit

E01A10465 96T
EUR 700
Description: ELISA

GAL4 Activation Domain Polyclonal Antibody

ABP57231-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of GAL4 Activation Domain from Human. This GAL4 Activation Domain antibody is for WB. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

GAL4 Activation Domain Polyclonal Antibody

ABP57231-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of GAL4 Activation Domain from Human. This GAL4 Activation Domain antibody is for WB. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

GAL4 Activation Domain Polyclonal Antibody

ABP57231-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of GAL4 Activation Domain from Human. This GAL4 Activation Domain antibody is for WB. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

GAL4 Activation Domain Polyclonal Antibody

ABP57231-100uL 100 μL
EUR 239
Description: Rabbit Anti-GAL4 Activation Domain Polyclonal Antibody

GAL4 Activation Domain Polyclonal Antibody

ABP57231-200uL 200 μL
EUR 379
Description: Rabbit Anti-GAL4 Activation Domain Polyclonal Antibody

GAL4 Activation Domain Polyclonal Antibody

ABP57231-30uL 30 μL
EUR 109
Description: Rabbit Anti-GAL4 Activation Domain Polyclonal Antibody

GAL4 Activation Domain Polyclonal Antibody

E20-53410 100ug
EUR 225
Description: Available in various conjugation types.

FAP Antibody / Fibroblast activation protein

RQ4022 100 ug
EUR 356.15
Description: Fibroblast activation protein alpha is a homodimeric 170 kDa melanoma membrane-bound gelatinase, protein that in humans is encoded by the FAP gene. The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

anti-Fibroblast activation protein, alpha

YF-PA11714 50 ug
EUR 435.6
Description: Mouse polyclonal to Fibroblast activation protein, alpha

anti-Fibroblast activation protein, alpha

YF-PA11715 100 ug
EUR 483.6
Description: Rabbit polyclonal to Fibroblast activation protein, alpha

GAL4 Activation Domain Polyclonal Antibody

E44H11033 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

B-Cell Activation Protein (CD83) Antibody

abx117184-100ug 100 ug
EUR 560.4

B-Cell Activation Protein (CD83) Antibody

abx146654-100ug 100 ug
EUR 526.8

B-Cell Activation Protein (CD83) Antibody

abx146735-100ug 100 ug
EUR 526.8

B-Cell Activation Protein (CD83) Antibody

20-abx134019
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ul
  • 200 ul
  • 50 ul

Current advances in myeloid-derived suppressor cell biology

In recent times, finding out the function of myeloid-derived suppressor cells (MDSCs) in lots of pathological inflammatory circumstances has grow to be a really energetic analysis space. Though the function of MDSCs in most cancers is comparatively nicely established, their function in non-cancerous pathological circumstances stays in its infancy leading to a lot confusion.

Our aims on this evaluate are to deal with some current advances in MDSC analysis to be able to decrease such confusion and to supply an perception into their perform within the context of different illnesses. The next subjects will likely be particularly centered upon: (1) definition and characterization of MDSCs; (2) whether or not all MDSC populations include immature cells;

(3) technical points in MDSC isolation, estimation and characterization; (4) the origin of MDSCs and their anatomical distribution in well being and illness; (5) mediators of MDSC growth and accumulation; (6) components that decide the growth of 1 MDSC inhabitants over the opposite; (7) the Yin and Yang roles of MDSCs. Furthermore, the features of MDSCs will likely be addressed all through the textual content.

novahep
novahep

MRGPRX2 alerts its significance in cutaneous mast cell biology: Does MRGPRX2 join mast cells and atopic dermatitis?

The invention of MRGPRX2 marks an essential change in MC biology, explaining non-IgE-mediated medical phenomena counting on MCs. As receptor for a number of medicine, MRGPRX2 is essential to drug-induced hypersensitivity.

Nevertheless, not solely medicine, but in addition endogenous mediators like neuropeptides and host protection peptides activate MRGPRX2, suggesting its broad affect in cutaneous pathophysiology. Right here, we give a quick overview of MRGPRX2 and its regulation by microenvironmental stimuli, which help MCs and will be altered in pores and skin issues, and briefly contact on the practical packages elicited by MRGPRX2 ligation. Research in Mrgprb2-deficient mice (the murine ortholog) assist illuminate MRGPRX2’s perform in well being and illness.

Current advances on this mannequin help the long-suspected operational unit between MCs and nerves, with MRGPRX2 being a significant part. Based mostly on the restricted proof for a serious contribution of FcεRI/IgE-activated MCs to atopic dermatitis (AD), we develop the speculation that MRGPRX2 constitutes the lacking hyperlink connecting MCs and AD, no less than in chosen endotypes. Assist comes from the multifold adjustments within the MC-neuronal system of AD pores and skin (e.g. higher density of MCs and nearer connections between MCs and nerves, elevated PAR-2/Substance P).

We theorize that these deregulations suffice to provoke AD, however exterior triggers, lots of which activating MRGPRX2 themselves (e.g. Staphylococcus aureus) additional feed into the loop. Itch, essentially the most burdensome hallmark of AD, is usually non-histaminergic however tryptase-dependent, and tryptase is preferentially launched upon MRGPRX2 activation. As a result of MRGPRX2 is a really energetic analysis discipline, a number of the present gaps are more likely to be closed quickly.

Manufacturing of a polyclonal antibody in opposition to inosine-uridine preferring nucleoside hydrolase of Acanthamoeba castellanii and its entry to analysis of Acanthamoeba keratitis

 

Acanthamoeba keratitis (AK) is a uncommon illness however its prevalence all through the globe continues to develop, primarily on account of elevated contact lens utilization. Since early-stage signs related to AK carefully resemble these from different corneal infections, correct analysis is tough and this usually ends in delayed therapy and exacerbation of the illness, which may result in everlasting visible impairment. Accordingly, growing a speedy Acanthamoeba-specific diagnostic technique is very desired.

Within the current examine, a speedy and differential technique for AK analysis was developed utilizing the secretory proteins derived from the pathogenic Acanthamoeba. Among the many huge portions of proteins secreted by the pathogenic Acanthamoeba, an open studying body of the inosine-uridine preferring nucleoside hydrolase (IPNH) gene was obtained.

After expressing and purifying the IPNH protein utilizing the pGEX 4T-Three vector system, mice have been immunized with the purified proteins for polyclonal antibody technology.

Western blot was carried out utilizing protein lysates of the human corneal cell, non-pathogenic amoeba, pathogenic amoeba, and medical amoeba isolate together with lysates from different causes of keratitis akin to Staphylococcus aureus, Pseudomonas aeruginosa, and Fusarium solani to verify Acanthamoeba-specificity.

Western blot utilizing the polyclonal IPNH antibody revealed that IPNH was Acanthamoeba-specific since these proteins have been solely noticed in lysates of Acanthamoeba origin or its tradition media. Our findings point out that the IPNH antibody of Acanthamoeba could function a possible agent for speedy and differential AK analysis.

, , , , , , , , , , , , , , , , , , , , , ,

Post navigation

Leave a Reply

Your email address will not be published. Required fields are marked *