Recent advances in myeloid-derived suppressor cell biology

Entosis: From Cell Biology to Medical Most cancers Pathology 

Entosis is a phenomenon, through which one cell enters a second one. New clinico-histopathological research of entosis prompted us to summarize its significance in most cancers. It seems that entosis is perhaps a novel, unbiased prognostic predictor think about most cancers histopathology.

We briefly talk about the organic foundation of entosis, adopted by a abstract of revealed clinico-histopathological research on entosis significance in most cancers prognosis. The correlation of entosis with most cancers prognosis in head and neck squamous cell carcinoma, anal carcinoma, lung adenocarcinoma, pancreatic ductal carcinoma and breast ductal carcinoma, is proven.

Quite a few entotic figures are related to a extra malignant most cancers phenotype and poor prognosis in lots of cancers. We additionally confirmed that some anticancer medicine may induce entosis in cell tradition, at the same time as an escape mechanism. Thus, entosis is probably going useful for survival of malignant cells, i.e., an entotic cell can disguise from unfavourable components in one other cell and subsequently depart the host cell remaining intact, resulting in failure in remedy or most cancers recurrence.

Lastly, we spotlight the potential relationship of cell adhesion with entosis in vitro, based mostly on the mannequin of the BxPc3 cells cultured in full adhesive circumstances, evaluating them to a generally used MCF7 semiadhesive mannequin of entosis.

 

H-Ras Activation Assay Kit, Trial Size

STA-400-H-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

K-Ras Activation Assay Kit, Trial Size

STA-400-K-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

N-Ras Activation Assay Kit, Trial Size

STA-400-N-T 5 assays
EUR 403
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

Rac1 Activation Assay

STA-401-1 20 assays
EUR 757
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Rac2 Activation Assay

STA-401-2 20 assays
EUR 757
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Cdc42 Activation Assay

STA-402 20 assays
EUR 757
Description: Our Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of Cdc42 protein. The precipitated small GTPase is then detected by Western blot using a Cdc42-specific antibody included in the kit.

RhoA Activation Assay

STA-403-A 20 assays
EUR 757
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoB Activation Assay

STA-403-B 20 assays
EUR 757
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoC Activation Assay

STA-403-C 20 assays
EUR 757
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

Arf1 Activation Assay

STA-407-1 20 assays
EUR 757
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Arf6 Activation Assay

STA-407-6 20 assays
EUR 757
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Ral Activation Assay

STA-408 20 assays
EUR 757
Description: Our Ral Activation Assay uses visible agarose beads to selectively precipitate the active form of Ral protein. The precipitated small GTPase is then detected by Western blot using a Ral-specific antibody included in the kit.

Ran Activation Assay

STA-409 20 assays
EUR 757
Description: Our Ran Activation Assay uses visible agarose beads to selectively precipitate the active form of Ran protein. The precipitated small GTPase is then detected by Western blot using a Ran-specific antibody included in the kit.

Pan-RAS-IN-1

HY-101295 25mg
EUR 1703

Rap1 Activation Assay Kit

STA-406-1 20 assays
EUR 757
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Rap2 Activation Assay Kit

STA-406-2 20 assays
EUR 757
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Rac1 Activation Assay Kit, Trial Size

STA-401-1-T 5 assays
EUR 403
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Rac2 Activation Assay Kit, Trial Size

STA-401-2-T 5 assays
EUR 403
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Cdc42 Activation Assay Kit, Trial Size

STA-402-T 5 assays
EUR 403
Description: Our Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of Cdc42 protein. The precipitated small GTPase is then detected by Western blot using a Cdc42-specific antibody included in the kit.

RhoA Activation Assay Kit, Trial Size

STA-403-A-T 5 assays
EUR 403
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoB Activation Assay Kit, Trial Size

STA-403-B-T 5 assays
EUR 403
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoC Activation Assay Kit, Trial Size

STA-403-C-T 5 assays
EUR 403
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

Rac1/Cdc42 Activation Assay Combo Kit

STA-404 2 x 20 assays
EUR 1088
Description: Our Rac1/Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of the small GTPase. The precipitated small GTPase is then detected by Western blot using a specific antibody included in the kit.

Rap1 Activation Assay Kit, Trial Size

STA-406-1-T 5 assays
EUR 403
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Rap2 Activation Assay Kit, Trial Size

STA-406-2-T 5 assays
EUR 403
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Arf1 Activation Assay Kit, Trial Size

STA-407-1-T 5 assays
EUR 403
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Arf6 Activation Assay Kit, Trial Size

STA-407-6-T 5 assays
EUR 403
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Ral Activation Assay Kit, Trial Size

STA-408-T 5 assays
EUR 403
Description: Our Ral Activation Assay uses visible agarose beads to selectively precipitate the active form of Ral protein. The precipitated small GTPase is then detected by Western blot using a Ral-specific antibody included in the kit.

Ran Activation Assay Kit, Trial Size

STA-409-T 5 assays
EUR 403
Description: Our Ran Activation Assay uses visible agarose beads to selectively precipitate the active form of Ran protein. The precipitated small GTPase is then detected by Western blot using a Ran-specific antibody included in the kit.

RhoA/Rac1/CDC42 Activation Assay Combo Kit

STA-405 3 x 10 assays
EUR 1088
Description: Our RhoA/Rac1/Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of the small GTPase. The precipitated small GTPase is then detected by Western blot using a specific antibody included in the kit.

96-Well Ras Activation ELISA Kit (Colorimetric)

STA-440 96 assays
EUR 902
Description: Our 96-Well Ras Activation ELISA Kit uses the Raf1 RBD (Rho binding domain) bound to a 96-well plate to selectively pull down the active form of Ras from purified or endogenous samples. The captured GTP-Ras is then detected by a pan-Ras antibody and HRP-conjugated secondary antibody.

96-Well Ras Activation ELISA Kit (Chemiluminescent)

STA-441 96 assays
EUR 902
Description: Our 96-Well Ras Activation ELISA Kit uses the Raf1 RBD (Rho binding domain) bound to a 96-well plate to selectively pull down the active form of Ras from purified or endogenous samples. The captured GTP-Ras is then detected by a pan-Ras antibody and HRP-conjugated secondary antibody.

Pan-PAX (Pan-PAX) Antibody

abx236136-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Cytokeratin, pan (Epithelial Marker); Clone PAN-CK (Concentrate)

RA0430-C.5 0.5 ml
EUR 300

pan-Cytokeratin antibody

23032-100ul 100ul
EUR 390

Keratin pan antibody

20R-2530 250 uL
EUR 510
Description: Rabbit polyclonal Keratin pan antibody

Synuclein pan antibody

70R-30766 100 ug
EUR 327
Description: Rabbit polyclonal Synuclein pan antibody

Actin pan antibody

70R-31095 100 ug
EUR 327
Description: Rabbit polyclonal Actin pan antibody

H3 Pan Antibody

6806-50
EUR 316

Synuclein-pan Antibody

33495-100ul 100ul
EUR 252

Synuclein-pan Antibody

33495-50ul 50ul
EUR 187

pan-AKT Antibody

36716-100ul 100ul
EUR 252

pan CDH Antibody

37301-100ul 100ul
EUR 252

pan-AKT antibody

38602-100ul 100ul
EUR 252

Actin-pan Antibody

33321-100ul 100ul
EUR 252

Actin-pan Antibody

33321-50ul 50ul
EUR 187

pan Cytokeratin antibody

10R-2060 100 ul
EUR 403
Description: Mouse monoclonal pan Cytokeratin antibody

Cytokeratin Pan antibody

10R-2096 100 ul
EUR 403
Description: Mouse monoclonal Cytokeratin Pan antibody

pan Keratin antibody

10R-2442 50 ug
EUR 405
Description: Mouse monoclonal pan Keratin antibody

LDH Pan antibody

10-1335 1 mg
EUR 259
Description: Mouse monoclonal LDH Pan antibody

LDH Pan antibody

10-1336 1 mg
EUR 259
Description: Mouse monoclonal LDH Pan antibody

pan Endothelium antibody

10R-6386 100 ug
EUR 284
Description: Mouse monoclonal pan Endothelium antibody

pan Cadherin antibody

10R-7890 100 ug
EUR 322
Description: Mouse monoclonal pan Cadherin antibody

Actin-pan antibody

10R-A106a 100 ug
EUR 553
Description: Mouse monoclonal Actin-pan antibody

Pan-Cadherin Antibody

48907-100ul 100ul
EUR 333

Pan-Cadherin Antibody

48907-50ul 50ul
EUR 239

pan Cadherin Antibody

45029-100ul 100ul
EUR 252

pan Cadherin Antibody

45029-50ul 50ul
EUR 187

pan Cadherin Antibody

45052-100ul 100ul
EUR 252

pan Cadherin Antibody

45052-50ul 50ul
EUR 187

Pan myristoylation Antibody

1-CSB-PA885152
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Description: A polyclonal antibody against Pan myristoylation. Recognizes Pan myristoylation from ALL. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1:500-10000, ELISA:1:10000

pan Cadherin Antibody

DF2942 200ul
EUR 304
Description: pan Cadherin Antibody detects endogenous levels of total pan Cadherin.

pan-AKT Antibody

DF7208 200ul
EUR 304
Description: pan-AKT Antibody detects endogenous levels of total pan-AKT.

pan Cadherin Antibody

DF7514 200ul
EUR 304
Description: pan Cadherin Antibody detects endogenous levels of total pan Cadherin.

Pan Methylated Lysine

DF7728 200ul
EUR 304
Description: Pan Methylated Lysine Rabbit pAbdetects endogenous levels of total Pan Methylated Lysine Rabbit pAb.

Pan myristoylation Antibody

1-CSB-PA465729
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Description: A polyclonal antibody against Pan myristoylation. Recognizes Pan myristoylation from ALL. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1:500-10000, ELISA:1:10000

FOXO1 pan antibody

70R-37057 100 ug
EUR 327
Description: Rabbit Polyclonal FOXO1 pan antibody

SSX pan antibody

70R-50426 100 ul
EUR 244
Description: Purified Polyclonal SSX pan antibody

NBPF pan antibody

70R-51031 100 ul
EUR 244
Description: Purified Polyclonal NBPF pan antibody

Melanoma; Pan (Concentrate)

A00134-C 1 ml
EUR 676

Melanoma; Pan (Concentrate)

A00134-C.1 0.1 ml
EUR 138

PKC pan antibody

70R-33408 100 ug
EUR 327
Description: Rabbit polyclonal PKC pan antibody

NBPF-pan Antibody

20-abx008107
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

SSX-pan Antibody

20-abx008681
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Pan pLDH Antibody

abx023860-1mg 1 mg
EUR 342
  • Shipped within 5-10 working days.

Pan pLDH Antibody

abx023861-1mg 1 mg
EUR 342
  • Shipped within 5-10 working days.

Pan SUMO Antibody

abx027085-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Pan SUMO Antibody

abx027085-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Pan SUMO Antibody

abx027140-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Pan SUMO Antibody

abx027140-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

pan Cadherin Antibody

abx217630-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.

Pan-AKT Antibody

20-abx125375
  • EUR 592.00
  • EUR 857.00
  • EUR 411.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

pan Cadherin Antibody

20-abx149140
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Actin-pan Antibody

20-abx013019
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Synuclein-pan Antibody

20-abx013202
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Actin-pan Antibody

AF0115 200ul
EUR 304
Description: Actin-pan antibody detects endogenous levels of total Actin-pan.

PKC-pan Antibody

AF6197 200ul
EUR 304
Description: PKC-pan Antibody detects endogenous levels of total PKC-pan.

Pan myristoylation Antibody

20-abx322788
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Pan myristoylation Antibody

20-abx322789
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Pan Ubiquitin Antibody

abx415347-50ug 50 ug
EUR 565
  • Shipped within 1 week.

pan ADH Antibody

abx433090-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

SHANK (pan) Antibody

abx440129-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx440140-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx440246-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx440410-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx440421-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx440527-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx440691-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx440702-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx440808-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx440972-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx440983-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx441089-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx441253-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx441264-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx441370-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx441534-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx441545-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx441651-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx441815-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx441826-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx441932-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx442096-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx442107-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx442213-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx442377-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx442388-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx442494-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx442658-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx442669-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx442775-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx442938-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx442949-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx443055-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx443218-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx443229-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx443335-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx443499-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx443510-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx443616-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx443780-100ug 100 ug
EUR 592
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx443791-100ug 100 ug
EUR 592
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx443897-100ug 100 ug
EUR 592
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx444061-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx444072-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx444178-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx444342-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx444353-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx444459-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx444623-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx444634-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx444740-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

SHANK (pan) Antibody

abx444980-100ug 100 ug
EUR 523
  • Shipped within 5-12 working days.

SAPAP (pan) Antibody

abx444991-100ug 100 ug
EUR 523
  • Shipped within 5-12 working days.

GRK (pan) Antibody

abx445060-100ug 100 ug
EUR 523
  • Shipped within 5-12 working days.

QKI (pan) Antibody

abx445076-100ug 100 ug
EUR 523
  • Shipped within 5-12 working days.

Ankyrin (pan) Antibody

abx445097-100ug 100 ug
EUR 523
  • Shipped within 5-12 working days.

PKC- pan Antibody

ABF6197 100 ug
EUR 438

pan Cadherin Antibody

ABD2942 100 ug
EUR 438

pan- AKT Antibody

ABD7208 100 ug
EUR 438

pan Cadherin Antibody

ABD7514 100 ug
EUR 438

Actin- pan Antibody

ABF0115 100 ug
EUR 438

Actin- pan Antibody

ABF5288 100 ug
EUR 438

pan-AKT Antibody

20-abx002260
  • EUR 411.00
  • EUR 592.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

anti-pan-Synuclein

LF-PA0194 100 ul
EUR 334
Description: Rabbit polyclonal to pan-Synuclein

Pan Keratin antibody

PAab09935 100 ug
EUR 386

pan Akt/KinaseB

MO15107 100 ug
EUR 435

NMDA NR1 Pan

MO25041 15 ug
EUR 592

RAS Antibody

31153-100ul 100ul
EUR 252

RAS Antibody

31153-50ul 50ul
EUR 187

RAS antibody

10R-1779 100 ul
EUR 349
Description: Mouse monoclonal RAS antibody

Ras Antibody

48578-100ul 100ul
EUR 333

Ras Antibody

48578-50ul 50ul
EUR 239

Ras Antibody

48602-100ul 100ul
EUR 333

Ras Antibody

48602-50ul 50ul
EUR 239

Ras Antibody

49408-100ul 100ul
EUR 333

Ras Antibody

49408-50ul 50ul
EUR 239

Rabbit Anti-Llama IgG (H+L chain), Antisera (Bulk)

30818-RAS-BLK 1-10L, bulk Ask for price

Rabbit Anti-Human IgG, Antisera (Bulk)

10119-RAS-BLK 1-10L, bulk Ask for price

Rabbit Anti-Goat IgG, Antisera (Bulk)

60319-RAS-BLK 1-10L, bulk Ask for price

Rabbit Anti-Mouse IgG, Antisera (Bulk)

44319-RAS-BLK 1-10L, bulk Ask for price

XTT CELL VIABILITY ASSAY KIT (1000 ASSAY)

30007 1KIT
EUR 236
Description: Minimum order quantity: 1 unit of 1KIT

Ras-Related Protein R-Ras (RRAS) Antibody

abx026316-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Ras-Related Protein R-Ras (RRAS) Antibody

abx026316-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Ras-related protein R-Ras (RRAS) Antibody

20-abx214133
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Ras-Related Protein M-Ras (MRAS) Antibody

20-abx113895
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Ras-Related Protein R-Ras (RRAS) Antibody

20-abx123552
  • EUR 495.00
  • EUR 356.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Ras-related protein R-Ras (RRAS) Antibody

20-abx241995
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Ras-Related Protein R-Ras (RRAS) Antibody

abx237489-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Ras-Related Protein R-Ras (RRAS) Protein

20-abx262883
  • EUR 328.00
  • EUR 6397.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg
  • Shipped within 5-10 working days.

Endothelial Tube Formation Assay (In Vitro Angiogenesis Assay)

CBA-200 50 assays
EUR 560
Description: For angiogenesis to occur, endothelial cells must escape their stable location and break through the basement membrane. Cells migrate toward an angiogenic stimulus that may be released from nearby tumor cells. These cells proliferate to form new blood vessels. Our Endothelial Tube Formation Assay (In Vitro Angiogenesis) provides an easy, robust system to assess angiogenesis in vitro. The ECM gel matrix very closely resembles an in vivo environment.

Monoclonal Cytokeratin, pan (Epithelial Marker) Antibody, Clone: PAN-CK (Cocktail)

APR14636G 7 ml
EUR 484
Description: A Monoclonal antibody against Human Cytokeratin, pan (Epithelial Marker). The antibodies are raised in Mouse and are from clone PAN-CK (Cocktail). This antibody is applicable in WB, IHC and IF, FC

Pan Acetyl-Lysine pAb

30416-100ul 100ul
EUR 252

Pan Acetyl-Lysine pAb

30416-50ul 50ul
EUR 187

Pan DiMethyl-lysine pAb

30669-100ul 100ul
EUR 252

Pan DiMethyl-lysine pAb

30669-50ul 50ul
EUR 187

Pan hair keratins antibody

20R-2654 100 uL
EUR 571
Description: Guinea Pig polyclonal pan hair keratins antibody

E cadherin pan antibody

70R-31124 100 ug
EUR 327
Description: Rabbit polyclonal E cadherin pan antibody

Anti- Myosin-pan Antibody

A1213-100
EUR 403

Anti-Keratin-pan Antibody

A05667 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Keratin-pan Antibody (KRT2) detection.tested for IHC, WB in Human, Mouse, Rat.

Current advances in myeloid-derived suppressor cell biology

In recent times, finding out the function of myeloid-derived suppressor cells (MDSCs) in lots of pathological inflammatory circumstances has grow to be a really energetic analysis space. Though the function of MDSCs in most cancers is comparatively nicely established, their function in non-cancerous pathological circumstances stays in its infancy leading to a lot confusion.

Our aims on this evaluate are to deal with some current advances in MDSC analysis to be able to decrease such confusion and to supply an perception into their perform within the context of different illnesses. The next subjects will likely be particularly centered upon: (1) definition and characterization of MDSCs; (2) whether or not all MDSC populations include immature cells;

(3) technical points in MDSC isolation, estimation and characterization; (4) the origin of MDSCs and their anatomical distribution in well being and illness; (5) mediators of MDSC growth and accumulation; (6) components that decide the growth of 1 MDSC inhabitants over the opposite; (7) the Yin and Yang roles of MDSCs. Furthermore, the features of MDSCs will likely be addressed all through the textual content.

novahep
novahep

MRGPRX2 alerts its significance in cutaneous mast cell biology: Does MRGPRX2 join mast cells and atopic dermatitis?

The invention of MRGPRX2 marks an essential change in MC biology, explaining non-IgE-mediated medical phenomena counting on MCs. As receptor for a number of medicine, MRGPRX2 is essential to drug-induced hypersensitivity.

Nevertheless, not solely medicine, but in addition endogenous mediators like neuropeptides and host protection peptides activate MRGPRX2, suggesting its broad affect in cutaneous pathophysiology. Right here, we give a quick overview of MRGPRX2 and its regulation by microenvironmental stimuli, which help MCs and will be altered in pores and skin issues, and briefly contact on the practical packages elicited by MRGPRX2 ligation. Research in Mrgprb2-deficient mice (the murine ortholog) assist illuminate MRGPRX2’s perform in well being and illness.

Current advances on this mannequin help the long-suspected operational unit between MCs and nerves, with MRGPRX2 being a significant part. Based mostly on the restricted proof for a serious contribution of FcεRI/IgE-activated MCs to atopic dermatitis (AD), we develop the speculation that MRGPRX2 constitutes the lacking hyperlink connecting MCs and AD, no less than in chosen endotypes. Assist comes from the multifold adjustments within the MC-neuronal system of AD pores and skin (e.g. higher density of MCs and nearer connections between MCs and nerves, elevated PAR-2/Substance P).

We theorize that these deregulations suffice to provoke AD, however exterior triggers, lots of which activating MRGPRX2 themselves (e.g. Staphylococcus aureus) additional feed into the loop. Itch, essentially the most burdensome hallmark of AD, is usually non-histaminergic however tryptase-dependent, and tryptase is preferentially launched upon MRGPRX2 activation. As a result of MRGPRX2 is a really energetic analysis discipline, a number of the present gaps are more likely to be closed quickly.

Manufacturing of a polyclonal antibody in opposition to inosine-uridine preferring nucleoside hydrolase of Acanthamoeba castellanii and its entry to analysis of Acanthamoeba keratitis

 

Acanthamoeba keratitis (AK) is a uncommon illness however its prevalence all through the globe continues to develop, primarily on account of elevated contact lens utilization. Since early-stage signs related to AK carefully resemble these from different corneal infections, correct analysis is tough and this usually ends in delayed therapy and exacerbation of the illness, which may result in everlasting visible impairment. Accordingly, growing a speedy Acanthamoeba-specific diagnostic technique is very desired.

Within the current examine, a speedy and differential technique for AK analysis was developed utilizing the secretory proteins derived from the pathogenic Acanthamoeba. Among the many huge portions of proteins secreted by the pathogenic Acanthamoeba, an open studying body of the inosine-uridine preferring nucleoside hydrolase (IPNH) gene was obtained.

After expressing and purifying the IPNH protein utilizing the pGEX 4T-Three vector system, mice have been immunized with the purified proteins for polyclonal antibody technology.

Western blot was carried out utilizing protein lysates of the human corneal cell, non-pathogenic amoeba, pathogenic amoeba, and medical amoeba isolate together with lysates from different causes of keratitis akin to Staphylococcus aureus, Pseudomonas aeruginosa, and Fusarium solani to verify Acanthamoeba-specificity.

Western blot utilizing the polyclonal IPNH antibody revealed that IPNH was Acanthamoeba-specific since these proteins have been solely noticed in lysates of Acanthamoeba origin or its tradition media. Our findings point out that the IPNH antibody of Acanthamoeba could function a possible agent for speedy and differential AK analysis.

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